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Photobiomodulation also called Low Level Laser Therapy (LLLT), Cold Laser Therapy, Laser Biostimulation, phototherapy or just Laser Therapy. Certain wavelengths of light at certain intensities (delivered by laser, LED or other monochromatic source), delivered for a certain amount of time will aid tissue regeneration, resolve inflammation, relive pain and boost the immune system. Clinical applications include soft tissue injuries, chronic pain, wound healing, nerve regeneration and possibly even resolve viral and bacterial infections. The exact mechanism is still being explored and debated but it is agreed that the mechanism is photochemical. This is not a heat therapy. Observed biological and physiological changes include cell membrane permeability, up-regulation and down-regulation of ATP and NOx. Contentious areas are, "best" wavelength, dose, dose-rate effects, beam penetration, the role of coherence and pulses (peak power and repetition rates). Laser average power is typically in the range of 1-500mW, some high peak short pulse width devices are in the range of 1W - 100W with typically 200nS pulse widths, average beam irradiance is typically 10mW/cm2 - 5W/cm2, wavelength is typically in the range 600nm - 1000nm but some research has been done and products are available outside this range. External links
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