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A laboratory centrifuge tabletop centrifuge A centrifuge is a piece of equipment that puts a substance in rotation around a fixed axis in order for the centrifugal force to separate a fluid from a fluid or from a solid substance. Generally, a motor drives the rotary motion of the sample. There are many different kinds of centrifuges, often for very specialised purposes.
TheoryProtocols for centrifugation typically specify the amount of acceleration to be applied to the sample, rather than specifying a rotational speed such as revolutions per minute. The acceleration is often specifed in multiples of g, the acceleration due to gravity on Earth. This distinction is important because two rotors with different diameters running at the same rotational speed will subject samples to different accelerations. The acceleration can be calculated as the product of the radius and the square of the angular velocity. History and predecessorsEnglish military engineer Benjamin Robins (1707-1751) invented a whirling arm apparatus to determine drag, and Antonin Prandl invented the first centrifuge in order to seperate cream from milk to make churning butter much easier. Different types and uses
Use and safetyThe load in a laboratory centrifuge must be carefully balanced. Small differences in mass of the load can result in a large force imbalance when the rotor is at high speed. This force imbalance strains the spindle and may result in damage to centrifuge or personal injury. Centrifuge rotors should never be touched while moving, because a spinning rotor can cause serious injury. Modern centrifuges generally have features that prevent accidental contact with a moving rotor. Because of the kinetic energy stored in the rotor head, those who have experienced an ultracentrifuge's losing a rotor compare the experience to having a bomb explode nearby. See also
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