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Cell signaling is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, we can treat diseases effectively and, potentially, build artificial tissues.

Cells receive information from their environment through a class of proteins known as receptors. The information is then processed through signaling pathways and decoded in the nucleus and other areas of the cell. Cell signaling research involves studying the spatial and temporal dynamics of both receptors and the components of signaling pathways to determine what parts are actually present in a given cell, where the parts are located, and what the parts are doing.

Traditional work in biology has focused on studying individual parts of cell signaling pathways. Systems biology research helps us understand the underlying structure of cell signaling networks and how changes in these networks can affect the transmission of information.

see signal transduction

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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "cell signaling".